Since 529 plans were designed to be helpful to the average American family, there are a lot of pluses.
They're flexible. The money in a 529 can be used for qualified expenses at just about any accredited college, university, or technical school in the U.S. And some of the 529 plans let students pay the cheaper "in-state resident" tuition rates, no matter what state they're from. One more benefit is that the 529 plan can be transferred if necessary, to certain family members of the beneficiary without penalty. So if one child doesn't use up all the money, you can still help your other children or even use it for your own education.
They're easy. You can use systematic deposits to add money to the 529 plan, or have money deducted from your paychecks. Anyone can contribute to the 529 plan, and deposits can be as little as $15.
They make good money sense. You won't pay federal income tax on the money that the investment earns. And most important, as the donor on the account, you retain control of the 529 plan even after the child turns 18. (So no matter how badly they want to use the money on a motorcycle or a road trip, you can make sure it gets used to fund their education.)